Merck Healthcare KGaA, Darmstadt, Germany
Part of Merck KGaA
CompanyGermanyFounded 2018
Merck Healthcare KGaA, Darmstadt, Germany develops 2 assets, the furthest approved (Mirdametinib). Mostly small molecule acting on MAP2K2, MAP2K1 and CSF1R; based in Germany, founded in 2018.
- 2
- Assets
- Furthest stage
- Approved
- 12
- Trials
- 5
- Signals
Pipeline
2Inhibits MEK1 and MEK2, reducing MAPK signaling and tumor growth.
Approved, Small molecule, MAP2K2, MAP2K1, neurofibromatosis type 1 (Phase 2), plexiform neurofibroma (Phase 2)
Inhibits CSF1R signaling to reduce tumor-associated macrophage proliferation and survival.
Phase 3, Small molecule, CSF1R, tenosynovial giant cell tumor
Full company profiles: pipeline, trials, funding and people.
In the full profile
- Evidence behind the mechanisms5
- Trials16
- Signals11
- Similar companies6
Papers
Metformin: Antidiabetic actions from cells to tissues
Metabolism: clinical and experimental, Mar 13, 2026
Vascular health and risk management, Mar 5, 2026
Combining Lifestyle With Metformin to Reduce Dementia Risk: Updates From MET-FINGER Trial
GSA 2025 abstract, Jan 3, 2026
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Aug 24, 2024
Journal of health economics and outcomes research, Dec 8, 2022
Journal of assisted reproduction and genetics, Mar 6, 2022
Digital biomarkers, Nov 26, 2020
Medicine, Nov 20, 2016