Institute for Research on Productive Aging

• Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in mice

  Board or leadership role, 24 Nov 2025

• Aging reduces motivation through decreased Bdnf expression in the ventral tegmental area

  Board or leadership role, 16 Sept 2025

• LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion

  Fees or honoraria, Patents or royalties, 17 Apr 2024

Sources: pubmed.ncbi.nlm.nih.gov

• Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signaling

  Cell metabolism, 9 May 2026