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NCT00716547
Phase 3, Completed, 1,399 people, Jul 16, 2008

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Jonathan, the 194-year-old tortoise, shows stable epigenetic regulation of metabolism and DNA repairResearchGEN and 7 more

Physical performance declines around 35, falling 30–48% below peak by 63ResearchScienceDaily and 5 more

Age-related decline in chaperone-mediated autophagy increases senescent cell burden, researchers reportResearchNature Aging

Trials

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and WomenResults posted Oct 13, 2026, Marquette University Benefits of Strength Training in Informal Caregivers of Patients With Alzheimer's DiseaseCompleted Oct 16, 2026, University of Salamanca Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical TrialPhase 2Registered Oct 13, 2026, University of Colorado, Boulder

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Mechanisms313 Interventions597 Biomarkers437 Populations704 AI & data124 Industry & policy20

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