Fondazione Telethon

• Elvira De Leonibus

  Lead investigator

Sources: openalex.org

• NCT04846335

  Collaborator, Phase 2, Completed, 29 people, 15 Apr 2021

• NCT03055247

  Collaborator, Phase 2, Recruiting, 3 people, 16 Feb 2017

• NCT01812551

  Collaborator, Phase 3, Completed, 171 people, 18 Mar 2013

• Alzheimer's Association

  SAGA, Neurobiology of sex differences in memory capacity in aging and Alzheimer's Disease, SAGA-17-418745, 2017, 1 Jan 2017

Sources: openalex.org

• Maria Marchese

  Long-term therapeutic and mechanistic evalUation of metformiN in zebrafish and pAtient-derived cell models for NCLs diseases (LUNA), telethon-934640, 2026–2027, 1 Jan 2026

• Elvira De Leonibus

  Targeting Early disease mechanisms in neurodegenerative disorders and the neurobiology of memory capacity, telethon-806625, 2022–2027, 1 Jan 2022

• Davide Cacchiarelli

  Integrative genomic approaches to understand human cell fate reprogramming in development and genetic diseases, telethon-806711, 2022–2027, 1 Jan 2022

• Raffaella Di Micco

  Cellular aging of hematopoietic stem cells in physiology and disease., telethon-806807, 2022–2026, 1 Jan 2022

• Francesco Trepiccione

  Treatment strategy with the SGLT2 inhibitor in a GSD1b mouse model to correct metabolite-repair deficiency affecting neutrophils and kidney function, telethon-807217, 2020–2022, 1 Jan 2020

• Raffaella Di Micco

  Aging in physiology and disease, telethon-807839, 2016–2021, 1 Jan 2016

• Davide Cacchiarelli

  Integrative genomic approaches to human cell fate reprogramming in development and genetic diseases, telethon-807828, 2016–2021, 1 Jan 2016

Sources: openalex.org

• The telomeric DNA damage response as a therapeutic target in idiopathic pulmonary fibrosis

  GMR23T2007, 12 Aug 2026

• Calorie Restriction Leads to Degradation of Mutant Uromodulin and Ameliorates Inflammation and Fibrosis in UMOD -Related Kidney Disease

  GMR23T2167, 3 Feb 2026

• Targeting C1q signaling in fibro-adipogenic progenitors prevents regenerative fibrosis of aged muscle

  GMR23T1221, 8 Jan 2026

• Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging

  TIGET Core Grant B2, TIGET Core Grant E5, 30 Dec 2025

• Spatiotemporal multi-omics atlas of the aging neuromuscular junction

  1 Dec 2025

• Recycling of ribosomes at stop codons drives the rate of translation and the transition from proliferation to RESt

  24 Nov 2025

• Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction

  GMR22T1055, 10 Nov 2025

• Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging

  GMR23T2152, 24 Sept 2025

• Sarcopenia: Aging-Related Loss of Muscle Mass and Function

  GGP14187c, 1 Jan 2019

• Autophagy is required to maintain muscle mass

  S04009, 1 Dec 2009

Sources: api.crossref.org, pubmed.ncbi.nlm.nih.gov