BridgeBio

Company

ROR

BridgeBio develops 3 assets, the furthest approved (infigratinib). Mostly small molecule acting on FGFR1, FGFR4 and fgfr3.

3
Assets
Furthest stage
Approved
6
Trials
2
Signals

Pipeline

3
  • Acoramidis

    Kinetic stabilizer of transthyretin tetramers preventing amyloidogenesis and fibril accumulation

    Approved, Small molecule, TTR, cardiac amyloidosis (Phase 3), amyloid (Phase 3)

  • infigratinib

    Inhibits FGFR tyrosine kinases, reducing excessive FGFR3 signaling that impairs bone growth in achondroplasia.

    Approved, Small molecule, FGFR1, FGFR4, advanced cholangiocarcinoma (Phase 3), fgfr2 gene mutation (Phase 3)

  • Encaleret

    Negative allosteric modulator (calcilytic) of the calcium-sensing receptor.

    Phase 3, Small molecule, autosomal dominant hypocalcemia

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Subsidiaries

3

In the full profile

  • Evidence behind the mechanisms7
  • Trials7
  • Signals11
  • Similar companies6

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