ZZW-115

Intervention1 paper2 findings

  • Cells1

Outcomes

2

Apoptosis

downin mouse cells1−55%Very low certainty

1 study

  1. ZZW-115 decreases apoptosis in mouse cells (-55%).

    Cellsin non-aged islets under high glucose conditionspancreatic islet

    Functional Analysis of NUPR1 in Age-Associated Changes in β-Cell Proliferation and Apoptosis · ADA Scientific Sessions 2025 abstract · 13 Jun 2025

Apoptosis →

EdU incorporation

upin mouse cells1Very low certainty

1 study

  1. ZZW-115 increases EdU incorporation in mouse cells (1.45-fold increase).

    Cellsin non-aged islets under high glucose conditionspancreatic islet

    Functional Analysis of NUPR1 in Age-Associated Changes in β-Cell Proliferation and Apoptosis · ADA Scientific Sessions 2025 abstract · 13 Jun 2025

EdU incorporation →

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