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Xpresso

Exposure

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 2 countries
  • Funders: Alzheimer's Drug Discovery Foundation and others
  • Humans1

Associations

3

Montreal Cognitive Assessment

upin humans1

1 study

  1. Xpresso is associated with Montreal Cognitive Assessment in humans (p < 0.005).

    “and between (2) XpressO sub-test scores and MoCA total score (p-values < 0.005).”

    Humansn = 86

    Montreal Cognitive Assessment (MoCA) XpressO: Validation of a digital self-administered cognitive prescreening tool

    Journal of the American Geriatrics Society1 Apr 2024

More on Montreal Cognitive Assessment

MoCA Memory Index Score

upin humans1

1 study

  1. Xpresso is associated with MoCA Memory Index Score in humans (p < 0.001).

    “Analysis showed strong correlation between (1) XpressO memory tasks scores and the MoCA Memory Index Score (p-values < 0.001)”

    Humansn = 86

    Montreal Cognitive Assessment (MoCA) XpressO: Validation of a digital self-administered cognitive prescreening tool

    Journal of the American Geriatrics Society1 Apr 2024

More on MoCA Memory Index Score

Abnormal MoCA score

upin humans1

1 study

  1. Xpresso predicts abnormal MoCA score in humans (AUC 0.845).

    “The AUC for predicting MoCA performance is 0.845.”

    Humansn = 86

    Montreal Cognitive Assessment (MoCA) XpressO: Validation of a digital self-administered cognitive prescreening tool

    Journal of the American Geriatrics Society1 Apr 2024

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