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Weizmannia coagulans extracellular vesicles

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Hokkaido University
  • 2 of 2 findings with company ties
  • Cells1

Outcomes

2

Mitochondrial biogenesis (PGC-1α)

upin human cells1

1 study

  1. Weizmannia coagulans extracellular vesicles increase mitochondrial biogenesis (PGC-1α) in human cells.

    “The addition of Lilac-01EVs to senescent human dermal fibroblasts suggested that Lilac-01 EVs increase the mitochondrial content without affecting their membrane potential in these cells.”

    Cellsin senescent cellsdermal fibroblast

    Extracellular vesicles of Weizmannia coagulans lilac-01 reduced cell death of primary microglia and increased mitochondrial content in dermal fibroblasts in vitro

    Bioscience, biotechnology, and biochemistryDec 21, 2023

More on Mitochondrial biogenesis (PGC-1α)

Cell death

downin rat cells1

1 study

  1. Weizmannia coagulans extracellular vesicles decrease cell death in rat cells (P < .05).

    “applying Lilac-01EVs to primary rat microglia in vitro resulted in a reduction in primary microglial cell death (P < .05)”

    Cellsmicroglia

    Extracellular vesicles of Weizmannia coagulans lilac-01 reduced cell death of primary microglia and increased mitochondrial content in dermal fibroblasts in vitro

    Bioscience, biotechnology, and biochemistryDec 21, 2023

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