Undertreatment
Undertreatment has been studied in 2 papers since 2021: 1 observational study in people, 1 review. The newest paper, Feb 27, 2024: “What are the consequences of over and undertreatment of type 2 diabetes mellitus in a frail population? A systematic review”.
See all 2 papers on undertreatment
At a glance
The findings reach people, from one lab or study. 2 independent labs in 2 countries.
“We found a considerably high proportion (53.3%) of undertreatment, which had a frailty-independent negative impact on the 5-year survival (hazard ratio [HR], 5.1; 95% confidence interval [CI], 2.1-12.5).”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funders: Centro de Investigação em Tecnologias e Serviços de Saúde and 2 more
- Humans1
What did studies of undertreatment find?
2Studies of undertreatment measured 2 outcomes: adverse outcomes and survival.
Adverse outcomes
upin humans1
1 study
Adverse outcomes
upin humans1
Undertreatment increases adverse outcomes in frail older people living with diabetes.
“both over and undertreatment were shown to increase adverse outcomes in frail older people.”
Reviewin frail older people living with diabetes
Endocrinology, diabetes & metabolism
Survival
downin humans1HR 5.1
1 study
Survival
downin humans1HR 5.1
Undertreatment is linked with lower survival in humans (breast cancer) (HR 5.1, 95% CI 2.1-12.5).
“We found a considerably high proportion (53.3%) of undertreatment, which had a frailty-independent negative impact on the 5-year survival (hazard ratio [HR], 5.1; 95% confidence interval [CI], 2.1-12.5).”
Humansbreast cancer5-year follow-upn = 92
Frailty-Independent Undertreatment Negative Impact on Survival in Older Patients With Breast Cancer
Journal of breast cancer