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Total lymphoid irradiation

Exposure

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Centre National d’Etudes Spatiales
  • Animals1

Outcomes

1

Lifespan

downin mice1−24%

1 study

  1. Total lymphoid irradiation shortens lifespan in mice (-24%).

    “There was a 24% shortening of life span.”

    Animals34 Gy17 daily fractions

    Late somatic effects in mice after total lymphoid irradiation

    Radiation research1 Dec 1988

Associations

3

Nephrosclerosis

upin mice1

1 study

  1. Total lymphoid irradiation raises the risk of nephrosclerosis in mice (38% vs 8%).

    “Furthermore, nephrosclerosis was a common finding in the irradiated group (38% vs 8%).”

    Animals34 Gy17 daily fractions

    Late somatic effects in mice after total lymphoid irradiation

    Radiation research1 Dec 1988

More on Nephrosclerosis

Malignant lymphoma

downin mice1

1 study

  1. Total lymphoid irradiation lowers the risk of malignant lymphoma in mice (6% vs 49%).

    “In contrast, the incidence of malignant lymphomas was greatly reduced in irradiated mice (6% vs 49%).”

    Animals34 Gy17 daily fractions

    Late somatic effects in mice after total lymphoid irradiation

    Radiation research1 Dec 1988

More on Malignant lymphoma

Solid tumor

upin mice1

1 study

  1. Total lymphoid irradiation raises the risk of solid tumor in mice (66% vs 30%).

    “A marked increase of solid tumor incidence, mostly due to skin cancers, was observed (66% vs 30%).”

    Animals34 Gy17 daily fractions

    Late somatic effects in mice after total lymphoid irradiation

    Radiation research1 Dec 1988

More on Solid tumor

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