Water fasting + tirzepatide

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Outcomes

Mobility

upin humans1

1 study

Water fasting + tirzepatide improves mobility in humans.
“He also experienced resolution of his chronic anemia, hypoxia, and leg wounds along with improved blood pressure, mobility, and decreased depressive symptoms.”
Human trialrefractory morbid obesity26 daysmalesn = 1
Combination of Prolonged Water Fasting and Tirzepatide for Treatment of Refractory Morbid Obesity: Case Report
AHA Scientific Sessions 2025 abstract3 Nov 2025

Left ventricular mass

downin humans1

1 study

Water fasting + tirzepatide decreases left ventricular mass in humans.
“Left ventricular mass also decreased significantly.”
Human trialrefractory morbid obesity26 daysmalesn = 1
Combination of Prolonged Water Fasting and Tirzepatide for Treatment of Refractory Morbid Obesity: Case Report
AHA Scientific Sessions 2025 abstract3 Nov 2025

Latest

1 in 12 months

AHA Scientific Sessions 2025 Abstract3 Nov

Combination of Prolonged Water Fasting and Tirzepatide for Treatment of Refractory Morbid Obesity: Case Report

Case reportTirzepatide

Paper

Water fasting + tirzepatide

Outcomes

Latest

Combination of Prolonged Water Fasting and Tirzepatide for Treatment of Refractory Morbid Obesity: Case Report

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