Targeted memory reactivation

1. Targeted memory reactivation improves item memory retention in humans.

   “amnestic patients benefited more from the intervention as they also had better item memory retention than controls.”

   Human trialamnestic Mild Cognitive Impairment patients

   Improvement of episodic memory retention by a memory reactivation intervention across the lifespan: from younger adults to amnesic patients

   Translational psychiatry·Apr 5, 2022

1. Targeted memory reactivation improves associative memory retention in humans.

   “Groups that underwent the reactivation-based intervention showed improved associative memory retention.”

   Human trialn = 150

   Improvement of episodic memory retention by a memory reactivation intervention across the lifespan: from younger adults to amnesic patients

   Translational psychiatry·Apr 5, 2022

1. Targeted memory reactivation increases late theta oscillations in humans.

   “Only in a later time window, theta oscillations were similarly increased during successful cueing for both young and older participants.”

   Human trialsuccessful cueing during sleep

   No effect of vocabulary reactivation in older adults

   Neuropsychologia·Aug 25, 2018

More on Late theta oscillations

1. Targeted memory reactivation has no effect on memory in humans.

   “In contrast to young participants, older adults' memories did not generally benefit from TMR during NREM sleep.”

   Human trialhealthy older adults during NREM sleep

   No effect of vocabulary reactivation in older adults

   Neuropsychologia·Aug 25, 2018