Aging Cell
Removing an enzyme eased kidney aging and bone loss in mice
Deleting the enzyme’s gene in kidney filtering cells reduced kidney damage and age-related bone loss in aged mice; a drug also improved kidney and bone measures.Deleting the enzyme’s gene in kidney filtering cells reduced kidney damage and age-related bone loss in aged mice; a drug also improved kidney and bone measures.
Mouse studyKidney
Who was studiedAged mice
What changedDeleting the enzyme’s gene in kidney filtering cells reduced kidney injury and age-related bone loss in aged mice
The catchThe drug experiment lasted two months, too short to assess long-term safety