Sulodexide

Intervention2 papers4 findings

  • Human trial1

Outcomes

4

Erectile function

upin humans1Very low certainty

1 study
  1. Sulodexide improves erectile function in humans (+14.8% (from 2.7 to 3.2)).

    Human trialstage IIa-IIb PAD500-1000 LSU6 monthsmales

    [Effect of sulodexide on the walking, erectile and cognitive functions based on the findings of the ANDANTE study] · Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery · 1 Jun 2026

Cognitive function

upin humans1Very low certainty

1 study
  1. Sulodexide improves cognitive function in humans (+12.2% (from 23.8 to 26.7 points)).

    Human trialstage IIa-IIb PAD500-1000 LSU6 monthsn = 229

    [Effect of sulodexide on the walking, erectile and cognitive functions based on the findings of the ANDANTE study] · Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery · 1 Jun 2026

Ankle-brachial index

upin humans1Very low certainty

1 study
  1. Sulodexide increases ankle-brachial index in humans (+10.0% (from 0.70 to 0.77)).

    Human trialstage IIa-IIb PAD500-1000 LSU6 monthsn = 229

    [Effect of sulodexide on the walking, erectile and cognitive functions based on the findings of the ANDANTE study] · Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery · 1 Jun 2026

Pain-free walking distance

upin humans1Very low certainty

1 study
  1. Sulodexide increases pain-free walking distance in humans (+72.4% (increment 237.1±434.6 m)).

    Human trialstage IIa-IIb PAD500-1000 LSU6 monthsn = 229

    [Effect of sulodexide on the walking, erectile and cognitive functions based on the findings of the ANDANTE study] · Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery · 1 Jun 2026

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