Science Advances
Oxidized molecule triggers brain inflammation in mice
Mouse experiments found that raising the molecule caused cognitive decline, while drugs blocking certain enzymes counteracted the induced inflammation and cognitive…Mouse experiments found that raising the molecule caused cognitive decline, while drugs blocking certain enzymes counteracted the induced inflammation and cognitive changes.
Mouse studyInflammation
Who was studiedMale SAMP8 mice, 2 months, against Nano vehicle
What changedMice treated with 8-oxoGTP had more activated microglia than controls
The catchOnly male mice were used, and sex differences may affect microglial activation in females