Smoking cessation pharmacotherapy

Intervention1 paper1 finding

  • Human trial1

Outcomes

1

Sustained tobacco abstinence

no changein humans1High certainty

1 study
  1. Smoking cessation pharmacotherapy has no effect on sustained tobacco abstinence in humans (difference, 0.5% [95% CI, -1.7% to 2.6%]).

    Human trialadded to ask-advise-refer compared with ask-advise-refer alonenicotine replacement and reimbursement for varenicline or bupropion6 monthsn = 3,220

    Financial incentives raise quit rates in underserved adults · JAMA · 5 Oct 2026

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JAMAHuman trial

Financial incentives raise quit rates in underserved adults

Six-month sustained abstinence reached 8.8% with incentives plus free medication, versus 4.3% with usual care and 5.1% with usual care plus free…Six-month sustained abstinence reached 8.8% with incentives plus free medication, versus 4.3% with usual care and 5.1% with usual care plus free medication.