AHA Scientific Sessions 2026 Abstract
Irregular sleep linked to heart and metabolic disease risk
An observational study followed 10,362 adults initially free of cardiovascular or metabolic disease for a median of three years, finding the broadest links with sleep…An observational study followed 10,362 adults initially free of cardiovascular or metabolic disease for a median of three years, finding the broadest links with sleep irregularity.

Cohort · 10,362 peopleMetabolic disease
Who was studied10,362 adults without cardiovascular or metabolic disease, median 3.0 years
What changedCardiovascular disease risk was higher with greater sleep duration variability (hazard ratio 1.24 per standard-deviation increase)
The catchUnmeasured health or lifestyle differences could contribute to the link between irregular sleep and disease