Sigma anti-bonding calcium

Intervention1 paper4 findings

Animals1

Outcomes

4

NFATC1

downin mouse cells1Very low certainty

1 study

Sigma anti-bonding calcium decreases NFATC1 in mouse cells.
Cellsin RANKL-stimulated RAW264.7 cells
Sigma Anti-bonding Calcium Attenuates Ovariectomy-Induced Bone Loss by Preserving Trabecular Microarchitecture and Suppressing Osteoclastogenesis · Calcified tissue international · 16 Sep 2026

Osteoclast differentiation

downin mouse cells1Very low certainty

1 study

Sigma anti-bonding calcium inhibits osteoclast differentiation in mouse cells.
Cellsin RANKL-induced RAW264.7 cells
Sigma Anti-bonding Calcium Attenuates Ovariectomy-Induced Bone Loss by Preserving Trabecular Microarchitecture and Suppressing Osteoclastogenesis · Calcified tissue international · 16 Sep 2026

CTX

downin mice1Very low certainty

1 study

Sigma anti-bonding calcium decreases CTX in mice.
Animalsin ovariectomized mice13 weeksfemales
Sigma Anti-bonding Calcium Attenuates Ovariectomy-Induced Bone Loss by Preserving Trabecular Microarchitecture and Suppressing Osteoclastogenesis · Calcified tissue international · 16 Sep 2026

Trabecular deterioration

downin mice1Very low certainty

1 study

Sigma anti-bonding calcium decreases trabecular deterioration in mice.
Animalsin ovariectomized mice13 weeksfemales
Sigma Anti-bonding Calcium Attenuates Ovariectomy-Induced Bone Loss by Preserving Trabecular Microarchitecture and Suppressing Osteoclastogenesis · Calcified tissue international · 16 Sep 2026

Latest

1

Calcified Tissue InternationalAnimals16 Sep

Sigma Anti-bonding Calcium Attenuates Ovariectomy-Induced Bone Loss by Preserving Trabecular Microarchitecture and Suppressing Osteoclastogenesis

Bones and joints