Open Forum Infectious Diseases
Semaglutide benefits partly faded in HIV-associated fat buildup
Among 108 people with HIV-associated fat buildup in a randomized trial, semaglutide recipients retained weight and waist reductions at week 56 after stopping at week 32.Among 108 people with HIV-associated fat buildup in a randomized trial, semaglutide recipients retained weight and waist reductions at week 56 after stopping at week 32.
Randomized trial · 80 peopleSemaglutide
Who was studied80 people with HIV-associated lipohypertrophy, against placebo recipients
What changedBody weight rose 5.8% after semaglutide stopped, while weight stayed relatively stable with placebo
The catchDiet and physical activity were not controlled and could contribute to weight regain