Self-reported visual difficulty

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country
1 finding against

Funders: Canadian Institutes of Health Research and 4 more

Humans1

Outcomes

Depression

no changein humans1OR 1.49

1 study

Self-reported visual difficulty has no effect on depression in humans (OR 1.49, 95% CI: 0.93-2.36).
“After exposure misclassification overlap weighting, self-reported vision was no longer associated with depression, and results mirrored the association between distance visual impairment and depression (OR 1.49, 95% CI: 0.93-2.36).”
Humansafter exposure misclassification overlap weighting
Harmonization of self-reported and performance-based measures of vision using inverse probability weighting: an example using vision and depression in NHATS, CLSA, and LASI
The journals of gerontology. Series A, Biological sciences and medical sciences30 Jan 2026

Associations

Depression

upin humans1OR 2.32

1 study

Self-reported visual difficulty is associated with depression in humans (adjusted OR 2.32, 95% CI: 1.46-3.69).
“Self-reported visual difficulty was associated with depression in NHATS (adjusted OR 2.32, 95% CI: 1.46-3.69)”
Humansunweighted/adjusted model
Harmonization of self-reported and performance-based measures of vision using inverse probability weighting: an example using vision and depression in NHATS, CLSA, and LASI
The journals of gerontology. Series A, Biological sciences and medical sciences30 Jan 2026

Latest

1 in 12 months

The Journals of Gerontology, Series A30 Jan

Harmonization of self-reported and performance-based measures of vision using inverse probability weighting: an example using vision and depression in NHATS, CLSA, and LASI

Cohort study of 2,447 peopleDepression

Paper

Self-reported visual difficulty

Outcomes

Associations

Latest

Harmonization of self-reported and performance-based measures of vision using inverse probability weighting: an example using vision and depression in NHATS, CLSA, and LASI

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