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Repeated cognitive testing

Exposure

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Center for Research Resources and 2 more
  • Humans1

Outcomes

2

RBANS score

no changein humans1

1 study

  1. Repeated cognitive testing has no effect on RBANS score in humans.

    “RBANS scores did not significantly change over time.”

    Human trial48 monthsn = 53

    Longitudinal Change in Performance on the Montreal Cognitive Assessment in Older Adults

    The Clinical neuropsychologist16 Sep 2015

Montreal Cognitive Assessment score

upin humans1

1 study

  1. Repeated cognitive testing increases montreal Cognitive Assessment score in humans.

    “Total MoCA score significantly increased across time, particularly between the first and second administrations.”

    Human trial48 monthsn = 53

    Longitudinal Change in Performance on the Montreal Cognitive Assessment in Older Adults

    The Clinical neuropsychologist16 Sep 2015

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