Psychoactive substance use
Intervention1 paper2 findings
- Humans1
Outcomes
1Mortality
upin humans1Low certainty
1 study
Mortality
upin humans1Low certainty
Psychoactive substance use increases mortality in humans (from 1.4 per 100,000 in 1999 to 4.16 in 2023).
HumansAMI-related premature mortality1999-2023n = 176,641
Premature mortality from acute myocardial infarction and psychoactive substance use in the United States: An observational trend (1999-2023) and forecasting (2035) study · JRSM cardiovascular disease · 1 Sep 2026
Associations
1Acute myocardial infarction
upin humans1
1 study
Acute myocardial infarction
upin humans1
Psychoactive substance use is associated with acute myocardial infarction in humans.
Reviewin premature death (<65 years)
Premature mortality from acute myocardial infarction and psychoactive substance use in the United States: An observational trend (1999-2023) and forecasting (2035) study · JRSM cardiovascular disease · 1 Sep 2026