Prebiotics + probiotics
Intervention1 paper2 findings
- Human trial1
Outcomes
2Fat-free mass
no changein humans1Very low certainty
1 study
Fat-free mass
no changein humans1Very low certainty
Prebiotics + probiotics have no effect on fat-free mass in humans.
Human trialperimenopausal women with migraine and intestinal dysbiosis6 monthsfemales
Fat-Free Mass Is Associated with Migraine Disability in Perimenopausal Women: A Pre-Specified Exploratory Analysis of the MEDEA Study · Preprints.org · 16 Sep 2026 · Preprint
Fat mass
downin humans1Very low certainty
1 study
Fat mass
downin humans1Very low certainty
Prebiotics + probiotics decrease fat mass in humans (median −3.00 kg at T6, p < 0.001).
Human trialperimenopausal women with migraine and intestinal dysbiosis6 monthsfemales
Fat-Free Mass Is Associated with Migraine Disability in Perimenopausal Women: A Pre-Specified Exploratory Analysis of the MEDEA Study · Preprints.org · 16 Sep 2026 · Preprint