Polynomial combination of T1-weighted and FLAIR MRI

Intervention1 paper2 findings

  • Humans1

Outcomes

2

Variance explained by age

upin silico1

1 study
  1. Polynomial combination of T1-weighted and FLAIR MRI increases variance explained by age in silico (R2 = .48 vs. R2 = .43, p < .001).

    In silicoin a model with age and age squaredn = 4,652

    An improved combination of T1-weighted and FLAIR contrasts for myelin water imaging · NeuroImage · 25 Aug 2026

Correlation with myelin water fraction

upin silico1

1 study
  1. Polynomial combination of T1-weighted and FLAIR MRI increases correlation with myelin water fraction in silico (r = .72 vs. r = .56, p < .01).

    In silicowhite matter

    An improved combination of T1-weighted and FLAIR contrasts for myelin water imaging · NeuroImage · 25 Aug 2026

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