Pomegranate + polygonum cuspidatum + trifolium pratense extract

Pomegranate + polygonum cuspidatum + trifolium pratense extract has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest paper, Feb 23, 2026: “Precision health targeting TMAO in postmenopausal women: polyphenol effects modulated by urolithin A and equol metabotypes in a randomised, placebo-controlled crossover trial”.

Intervention

1 paper studies it2 findingsUpdated

“the intervention reduced urinary TMAO and DMA versus baseline and placebo”
Precision health targeting TMAO in postmenopausal women: polyphenol effects modulated by urolithin A and equol metabotypes in a randomised, placebo-controlled crossover trialFood & function2026doi:10.1039/d5fo05461c

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Agencia Estatal de Investigación and 5 more
  • Human trial1

What did studies of Pomegranate + polygonum cuspidatum + trifolium pratense extract find?

2

Studies of Pomegranate + polygonum cuspidatum + trifolium pratense extract measured 2 outcomes; the most studied are dimethylamine (1 study) and TMAO (1).

Dimethylamine

downin humans1

1 study
  1. Pomegranate + polygonum cuspidatum + trifolium pratense extract decreases dimethylamine in humans.

    “intervention reduced urinary TMAO and DMA versus baseline and placebo”

    Human trialpostmenopausal women

    Precision health targeting TMAO in postmenopausal women: polyphenol effects modulated by urolithin A and equol metabotypes in a randomised, placebo-controlled crossover trial

    Food & function

More on Dimethylamine

TMAO

downin humans1

1 study
  1. Pomegranate + polygonum cuspidatum + trifolium pratense extract decreases TMAO in humans.

    “the intervention reduced urinary TMAO and DMA versus baseline and placebo”

    Human trialpostmenopausal women

    Precision health targeting TMAO in postmenopausal women: polyphenol effects modulated by urolithin A and equol metabotypes in a randomised, placebo-controlled crossover trial

    Food & function

More on TMAO

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months