Pneumococcal polysaccharide vaccine
Intervention1 paper3 findings
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Outcomes
3Mortality
no changein humans1HR 1.02
1 study
Mortality
no changein humans1HR 1.02
Pneumococcal polysaccharide vaccine has no effect on mortality in humans (HR 1.02, 95% CrI 0.83-1.29).
Humans
PPV23 Vaccination and Risk of Cardiovascular Events: A Meta-Analysis · JACC. Advances · 17 Aug 2026
Stroke
no changein humans1HR 1.1
1 study
Stroke
no changein humans1HR 1.1
Pneumococcal polysaccharide vaccine has no effect on stroke in humans (HR 1.10, 95% CrI 0.83-1.48).
Humans
PPV23 Vaccination and Risk of Cardiovascular Events: A Meta-Analysis · JACC. Advances · 17 Aug 2026
Acute coronary syndrome
no changein humans1HR 0.87
1 study
Acute coronary syndrome
no changein humans1HR 0.87
Pneumococcal polysaccharide vaccine has no effect on acute coronary syndrome in humans (HR 0.87, 95% CrI 0.64-1.14).
Humans
PPV23 Vaccination and Risk of Cardiovascular Events: A Meta-Analysis · JACC. Advances · 17 Aug 2026