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Plant-sourced ultra-processed foods

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 2 more
  • Humans1

Associations

1

Mortality

upin humans1

1 study

  1. Plant-sourced ultra-processed foods raise the risk of mortality in humans (4%-17% higher risk).

    “Similarly, per SD, higher intake of plant- and animal-sourced UPFs was associated with a 4%-17% higher risk of all-cause mortality, non-CVD related mortality, and cancer mortality.”

    Humansper standard deviation higher intakemedian follow-up of 10 yn = 2,582

    Ultra-processed foods, plant and animal sources, and all-cause, cardiovascular, and cancer mortality in older adults in the United States: results from the Cardiovascular Health Study

    The American journal of clinical nutrition2 Jun 2025

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