Phenylbutyrate

Intervention1 paper1 finding

  • Model organisms1

Outcomes

1

Maximum running time

upin A. domesticus1Very low certainty

1 study
  1. Phenylbutyrate improves maximum running time in A. domesticus (d = -2.30 to -1.32, P < 0.0001).

    “Rapamycin and phenylbutyrate extended maximum running time (d = -2.30 to -1.32, P < 0.0001)”

    Model organismstreadmill performance after 2-week intermittent dosing2-week

    The house cricket (Acheta domesticus) as a scalable invertebrate model for gerotherapeutic testing · GSA 2025 abstract · 31 Dec 2025

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