Phentermine-topiramate

Phentermine-topiramate has been studied in 15 papers since 2017: 3 observational studies in people, 11 reviews; 6 in the past year. The newest paper, Jun 8, 2026: “Risk of Age-Related Ocular Diseases in Non-Diabetic Adults With Obesity Using Glucagon-Like Peptide 1 Receptor Agonists”.

Intervention

15 papers study it1 findingUpdated

See all 15 papers on phentermine-topiramate

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country; 19 trials, none about aging, 2 with no results posted.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • 19 trials, none about aging, 2 with no results posted
  • 10 of 19 trials sponsored by its developers
  • Humans3
  • In silico1

What is phentermine-topiramate linked with?

1

Studies link phentermine-topiramate with Cost-effectiveness.

Cost-effectiveness

upin reviews1

1 study
  1. Phentermine-topiramate is associated with cost-effectiveness (particularly in low-resource settings).

    “Phentermine-topiramate showed acceptable cost-effectiveness, particularly in low-resource settings.”

    Reviewparticularly in low-resource settings

    Economic Evaluation of Medications in Prevention and Treatment of Obesity: A Systematic Review

    International journal of preventive medicine

Has phentermine-topiramate been tested in people?

0 of 19 about aging

Yes: 3 observational studies in people have been published, and 12 trials are registered.

In trials

All 11

Stopped

  • NCT04531176TerminatedObesity

    After an unplanned yet IRB approved interim analysis, it was found that there was not a significant difference between the 3 arms of the study. The study was closed due to futility. All Patients are off study and this study will not resume.

Trial sponsors

Latest

Dec 2025: 1Jan 2026: 0Feb 2026: 0Mar 2026: 2Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 04 papers in 12 months

See all 15 papers on phentermine-topiramate