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Pharmacological targeting of pdgfrβ signaling

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: American Federation for Aging Research and 3 more
  • Animals1

Outcomes

1

Beige adipocyte development

upin mice1

1 study

  1. Pharmacological targeting of pdgfrβ signaling improves beige adipocyte development in mice.

    “pharmacologically targeting Pdgfrβ signaling restores beige adipocyte development by rejuvenating the immunological niche”

    Animals

    Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice

    Nature communicationsMar 31, 2023

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