Perfluorobutanoic acid
Intervention1 paper3 findings
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funder: National Natural Science Foundation of China
- Humans1
Outcomes
2Antral follicle count
downin humans1
1 study
Antral follicle count
downin humans1
Perfluorobutanoic acid decreases antral follicle count in humans.
Humansfollicular fluidfemales
Exposure to Legacy and Novel Per- and Polyfluoroalkyl Substances and Diminished Ovarian Reserve: Evidence from Blood-Follicle Transfer and Mixture Risk Assessment in Reproductive-Aged Women · Environment & health (Washington, D.C.) · 16 Apr 2026
anti-Müllerian hormone
downin humans1
1 study
anti-Müllerian hormone
downin humans1
Perfluorobutanoic acid decreases anti-Müllerian hormone in humans.
Humansfollicular fluidfemales
Exposure to Legacy and Novel Per- and Polyfluoroalkyl Substances and Diminished Ovarian Reserve: Evidence from Blood-Follicle Transfer and Mixture Risk Assessment in Reproductive-Aged Women · Environment & health (Washington, D.C.) · 16 Apr 2026
Associations
1Diminished ovarian reserve
upin humans1
1 study
Diminished ovarian reserve
upin humans1
Perfluorobutanoic acid raises the risk of diminished ovarian reserve in humans.
Humanselevated follicular concentrationsfollicular fluidfemales
Exposure to Legacy and Novel Per- and Polyfluoroalkyl Substances and Diminished Ovarian Reserve: Evidence from Blood-Follicle Transfer and Mixture Risk Assessment in Reproductive-Aged Women · Environment & health (Washington, D.C.) · 16 Apr 2026