AgingResearch.NewsJoin free

Pcc1-p/l nps

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Key Research and Development Program of Zhejiang Province and 1 more
  • Model organisms1

Outcomes

4

Procyanidin C1

upin flies1

1 study

  1. Pcc1-p/l nps increase procyanidin C1 in flies (twofold).

    “It significantly increased the PCC1 concentrations in the intestine by twofold.”

    Model organismsintestine

    A novel yolk-shell nanoparticles delivery system based on Polygonatum polysaccharides and PCC1 for synergistic anti-aging

    Food research international (Ottawa, Ont.)5 Aug 2025

More on Procyanidin C1

pH 3+ cells

downin flies1

1 study

  1. Pcc1-p/l nps decrease pH 3+ cells in flies.

    “Moreover, the delivery system potently suppressed the accumulation of pH 3+ and esg + cells and preserved gut integrity.”

    Model organismsintestine

    A novel yolk-shell nanoparticles delivery system based on Polygonatum polysaccharides and PCC1 for synergistic anti-aging

    Food research international (Ottawa, Ont.)5 Aug 2025

Esg + cells

downin flies1

1 study

  1. Pcc1-p/l nps decrease esg + cells in flies.

    “Moreover, the delivery system potently suppressed the accumulation of pH 3+ and esg + cells and preserved gut integrity.”

    Model organismsintestine

    A novel yolk-shell nanoparticles delivery system based on Polygonatum polysaccharides and PCC1 for synergistic anti-aging

    Food research international (Ottawa, Ont.)5 Aug 2025

Lifespan

upin flies1+31% maximum lifespan

1 study

  1. Pcc1-p/l nps extend lifespan in flies (+30.8% maximum lifespan).

    “extending the maximum lifespan of Drosophila by 30.8 %, which significantly exceeded the effect of PCC1 or PSP alone.”

    Model organisms

    A novel yolk-shell nanoparticles delivery system based on Polygonatum polysaccharides and PCC1 for synergistic anti-aging

    Food research international (Ottawa, Ont.)5 Aug 2025

Latest

Related