Neighborhood segregation

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 1 country

Humans2

Outcomes

Chronic conditions and functional limitations trajectories

no changein humans1

1 study

Neighborhood segregation has no effect on chronic conditions and functional limitations trajectories in humans.
“for Black participants, the baseline level of black segregation does not significantly impact their trajectories in these health outcomes”
Humansamong Black participants
A LIFE COURSE APPROACH TO NEIGHBORHOOD SEGREGATION AND HEALTH AMONG BLACK AND WHITE AMERICANS
GSA 2024 abstract31 Dec 2024

Associations

Subjective cognitive decline

upin humans1

1 study

Neighborhood segregation is associated with subjective cognitive decline in humans.
“However, at moderate (p = .038) and high (p = .004) levels of active coping, greater neighborhood segregation was associated with increased SCD.”
Humansat moderate and high levels of active copingmalesn = 94
Active Coping Moderates the Link Between Neighborhood Segregation & Cognitive Decline in Black American Men
GSA 2025 abstract31 Dec 2025

Functional limitations

upin humans1

1 study

Neighborhood segregation is associated with functional limitations in humans.
“residing in neighborhoods with lower levels of white segregation is associated with an increased probability of developing more chronic conditions and experiencing functional limitations later in life”
Humansamong White participants
A LIFE COURSE APPROACH TO NEIGHBORHOOD SEGREGATION AND HEALTH AMONG BLACK AND WHITE AMERICANS
GSA 2024 abstract31 Dec 2024

Chronic conditions

upin humans1

1 study

Neighborhood segregation is associated with chronic conditions in humans.
“residing in neighborhoods with lower levels of white segregation is associated with an increased probability of developing more chronic conditions and experiencing functional limitations later in life”
Humansamong White participants
A LIFE COURSE APPROACH TO NEIGHBORHOOD SEGREGATION AND HEALTH AMONG BLACK AND WHITE AMERICANS
GSA 2024 abstract31 Dec 2024