Neighborhood poverty
Intervention2 papers7 findings
- Humans2
Outcomes
2Horvath clock
no changein humans2Low certainty
2 studies
Horvath clock
no changein humans2Low certainty
Neighborhood poverty has no effect on Horvath clock in humans.
“living in higher poverty neighborhoods was associated with accelerated PhenoAge and GrimAge (not Hannum or Horvath), adjusting for age, sex, and educational.”
Humansadjusting for age, sex, and educationaln = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
Neighborhood poverty has no effect on Horvath clock in humans.
“living in higher poverty neighborhoods was associated with accelerated PhenoAge and GrimAge (not Hannum or Horvath)”
Humansadjusting for age, sex, and educationn = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
Hannum's clock
no changein humans1Low certainty
1 study
Hannum's clock
no changein humans1Low certainty
Neighborhood poverty has no effect on Hannum's clock in humans.
“living in higher poverty neighborhoods was associated with accelerated PhenoAge and GrimAge (not Hannum or Horvath), adjusting for age, sex, and educational.”
Humansadjusting for age, sex, and educationaln = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
Associations
2PhenoAge
upin humans2Low certainty
2 studies
PhenoAge
upin humans2Low certainty
Neighborhood poverty is associated with PhenoAge in humans.
“living in higher poverty neighborhoods was associated with accelerated PhenoAge and GrimAge (not Hannum or Horvath), adjusting for age, sex, and educational.”
Humansadjusting for age, sex, and educationaln = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
Neighborhood poverty is associated with PhenoAge in humans.
“Results of weighted linear regressions suggested that living in higher poverty neighborhoods was associated with accelerated PhenoAge and GrimAge (not Hannum or Horvath), adjusting for age, sex, and educational.”
Humansadjusting for age, sex, and educationn = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
GrimAge
upin humans2Low certainty
2 studies
GrimAge
upin humans2Low certainty
Neighborhood poverty is associated with GrimAge in humans.
“After further considering smoking status, however, only the association with GrimAge remained.”
Humansadjusting for age, sex, education, and smoking statusn = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025
Neighborhood poverty is associated with GrimAge in humans.
“After further considering smoking status, however, only the association with GrimAge remained.”
Humansadjusting for age, sex, education, and smoking statusn = 3,790
Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison · GSA 2025 abstract · 31 Dec 2025