Neighborhood-level social vulnerability

1. Neighborhood-level social vulnerability impairs physical function in humans.

   “higher SVI scores were associated with lower levels of global cognitive and motor functioning-specifically, episodic memory, motor dexterity and gait”

   Humansin non-Latino Black older adultsn = 590

   Neighborhood-level social vulnerability and individual-level cognitive and motor functioning over time in older non-Latino Black and Latino adults

   Frontiers in human neuroscience·May 12, 2023

1. Neighborhood-level social vulnerability impairs cognitive function in humans.

   “For non-Latino Black participants, higher SVI scores were associated with lower levels of global cognitive and motor functioning”

   Humansin non-Latino Black older adultsn = 590

   Neighborhood-level social vulnerability and individual-level cognitive and motor functioning over time in older non-Latino Black and Latino adults

   Frontiers in human neuroscience·May 12, 2023

1. Neighborhood-level social vulnerability raises the risk of major adverse cardiovascular events in humans (HR=1.30 [95% CI, 1.23–1.37]).

   “compared to neighborhood SVI burden (HR, Q4 vs Q1=1.30 [95% CI, 1.23–1.37])”

   HumansQ4 vs Q1n = 168,304

   Individual Social Determinants of Health, Area-Level Social Vulnerability and Incidence of Major Adverse Cardiovascular Events in a Primary Prevention Population: Real-World Evidence from The Houston Methodist CV Learning Health System (HM-CV-LHS) Registry

   AHA Scientific Sessions 2025 abstract·Nov 3, 2025

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