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Multinutrient feed

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country

Outcomes

2

Mortality

no changein humans1RR 0.85

1 study

  1. Multinutrient feed has no effect on mortality in humans (12/91 versus 14/97; RR 0.85, 95% CI 0.42 to 1.70).

    “did not demonstrate an effect on mortality (12/91 versus 14/97; relative risk 0.85, 95% confidence interval 0.42 to 1.70)”

    Reviewhip fracture aftercare

    Nutritional supplementation for hip fracture aftercare in the elderly

    The Cochrane database of systematic reviews1 Jan 2004

Death or complications

downin humans1RR 0.52

1 study

  1. Multinutrient feed decreases death or complications in humans (14/66 versus 26/73; RR 0.52, 95% CI 0.32 to 0.84).

    “Oral multinutrient feeds (providing non-protein energy, protein, some vitamins and minerals), evaluated by seven trials, may reduce unfavourable outcome (death or complications) (14/66 versus 26/73; relative risk 0.52, 95% confidence interval 0.32 to 0.84)”

    Reviewhip fracture aftercare

    Nutritional supplementation for hip fracture aftercare in the elderly

    The Cochrane database of systematic reviews1 Jan 2004

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