Multi-cancer early detection screening
Intervention1 paper2 findings
- In silico1
Outcomes
1Cancer mortality
downin silico1Very low certainty
1 study
Cancer mortality
downin silico1Very low certainty
Multi-cancer early detection screening decreases cancer mortality in silico (41.0% reduction; 6.42% to 3.79% of the simulated population).
In silicoSimulated population under ideal early detection
Projected impact of population-level multi-cancer early detection screening: a discrete event simulation analysis · Journal of the National Cancer Institute · 6 Oct 2026
Associations
1Cancer overdiagnosis
upin silico1Very low certainty
1 study
Cancer overdiagnosis
upin silico1Very low certainty
Multi-cancer early detection screening is associated with cancer overdiagnosis in silico (10.9%–28.9% overdiagnosis; highest for lung cancer).
In silicoSimulated multi-cancer early detection screening
Projected impact of population-level multi-cancer early detection screening: a discrete event simulation analysis · Journal of the National Cancer Institute · 6 Oct 2026