ML-23

1. ML-23 increases 125I-melatonin binding sites in rats.

   “ML-23 treatment greatly increased 125I-melatonin binding in the medulla-pons whereas this increase was prevented by melatonin supplementation.”

   Animalsdrinking watermedulla-pons16 months

   Effects of long-term administration of melatonin and a putative antagonist on the ageing rat

   Neuroreport·Mar 27, 1995

More on 125I-melatonin binding sites

1. ML-23 extends lifespan in rats.

   “Surprisingly, ML-23 without or with melatonin, also prolonged the life-span of the aged animals.”

   Animalsdrinking water16 months

   Effects of long-term administration of melatonin and a putative antagonist on the ageing rat

   Neuroreport·Mar 27, 1995