Minicafe

1. Minicafe increases FGF21 in mice.

   “delivered within an all-in-one adeno-associated virus (AAV), miniCAFE can activate Fgf21 expression in the liver”

   Animalsall-in-one adeno-associated virusliver

   MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression in vivo

   Nucleic acids research·19 Apr 2021

More on FGF21

1. Minicafe extends lifespan in worms.

   “is able to promote lifespan of Caenorhabditis elegans through activation of longevity-regulating genes.”

   Model organisms

   MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression in vivo

   Nucleic acids research·19 Apr 2021