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Maternal hypoxia

Intervention

2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country

Outcomes

1

Skeletal muscle cellular and mitochondrial damage

upin rats1

1 study

  1. Maternal hypoxia increases skeletal muscle cellular and mitochondrial damage in rats.

    “revealed impaired cellular structures and mitochondria in the longitudinal sections of skeletal muscle from HY group mice”

    Animalsoffspring exposed to maternal hypoxia during pregnancyskeletal musclemales

    The SIRT3/GSK-3β/GLUT4 axis might be involved in maternal hypoxia-induced skeletal muscle insulin resistance in old male rat offspring

    Toxicology and applied pharmacology29 Jun 2024

Associations

1

Gsk3b and Slc2a4 expression

mixedin rats1

1 study

  1. Maternal hypoxia is associated with Gsk3b and Slc2a4 expression in rats.

    “Furthermore, the expression of insulin signaling molecules, such as GSK-3β and GLUT4, was also altered.”

    Animalsoffspring exposed to maternal hypoxia during pregnancyskeletal musclemales

    The SIRT3/GSK-3β/GLUT4 axis might be involved in maternal hypoxia-induced skeletal muscle insulin resistance in old male rat offspring

    Toxicology and applied pharmacology29 Jun 2024

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