Magnetic resonance-guided focused ultrasound thalamotomy
Magnetic resonance-guided focused ultrasound thalamotomy has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest paper, Mar 11, 2026: “Magnetic resonance-guided focused ultrasound thalamotomy in essential tremor subtypes: a phenotype-based insight into gait and balance”.
1 paper studies it4 findingsUpdated
“At 12 months, tandem gait remained stable in 87% of patients, and no significant differences emerged between groups.”
None of its findings points the other way.
- 1 lab in 1 country
- 4 of 4 findings with company ties
- Human trial1
Studies in people
1 study gave magnetic resonance-guided focused ultrasound thalamotomy to people and measured what changed.
up: Improves tremor
no change: Has no effect on gait stability
Trial81 people48 patients were male (59.3%)median age 73 years (range: 45–86 years)12 months
Patients with medically refractory tremor causing significant impairment in daily function
Brain communications, Mar 11, 2026
What did studies of Magnetic resonance-guided focused ultrasound thalamotomy find?
2Studies of Magnetic resonance-guided focused ultrasound thalamotomy measured 2 outcomes; the most studied are gait stability (1 study) and tremor (1).
Gait stability
no changein humans1
1 study
Gait stability
no changein humans1
Magnetic resonance-guided focused ultrasound thalamotomy showed no clear effect on gait stability in humans (unilateral MRgFUS VIM thalamotomy).
“At 12 months, tandem gait remained stable in 87% of patients, and no significant differences emerged between groups.”
Human trialunilateral MRgFUS VIM thalamotomy12 months
Brain communications
Magnetic resonance-guided focused ultrasound thalamotomy showed no clear effect on gait stability in humans (stable in 87% of patients).
“Tandem gait remained stable in 87% of patients at 12 months, with gait worsening being infrequent and generally mild”
Human trial12 monthsn = 76
Brain communications
Tremor
upin humans1
1 study
Tremor
upin humans1
Magnetic resonance-guided focused ultrasound thalamotomy improves tremor in humans (unilateral MRgFUS VIM thalamotomy).
“In the overall cohort, significant improvements were observed in the HTS, total CRST, and disability scores at both 6 and 12 months (P < 0.001 for all comparisons).”
Human trialunilateral MRgFUS VIM thalamotomy12 monthsn = 61
Brain communications
Magnetic resonance-guided focused ultrasound thalamotomy improves tremor in humans (improved by 80% in ET, 70% in ET-I, and 71% in DT).
“At 6 months, treated hand tremor score improved by 80% in ET, 70% in ET-I, and 71% in DT.”
Human trial6 monthsn = 76
Brain communications