Aging Cell
Human cells in long-term culture mirror features of aging
Experiments in four female fibroblast lines tracked molecular changes that resembled key features of aging in cells from the body.Experiments in four female fibroblast lines tracked molecular changes that resembled key features of aging in cells from the body.
Human cell studyInterventions
Who was studied4 human skin fibroblasts from female donors, 6 months
What changedCultured fibroblasts mirrored donor aging in 60 of the 66 declining pathways and 20 of the 31 rising pathways
The catchUncorrected tests in the smaller comparison cohort could inflate apparent overlap in aging pathways