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Live-life program

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Human trial1

Outcomes

4

Muscle strength

upin humans1

1 study

  1. Live-life program improves muscle strength in humans (d = 0.776, P = 0.002).

    “Significant improvements were observed on the total scores (P< 0.001, d=1.260), balance function dimension scores (P< 0.001, d=0.962), and strength function dimension scores (P=0.002, d=0.776).”

    Human trialcommunity-dwelling older adults11 weeksn = 20

    PILOT OUTCOMES OF A FALL PREVENTION PROGRAM “LIVE-LIFE” FOR COMMUNITY-DWELLING OLDER ADULTS IN CHINA

    GSA 2024 abstract31 Dec 2024

Balance

upin humans1

1 study

  1. Live-life program improves balance in humans (d = 0.962, P < 0.001).

    “Significant improvements were observed on the total scores (P< 0.001, d=1.260), balance function dimension scores (P< 0.001, d=0.962), and strength function dimension scores (P=0.002, d=0.776).”

    Human trialcommunity-dwelling older adults11 weeksn = 20

    PILOT OUTCOMES OF A FALL PREVENTION PROGRAM “LIVE-LIFE” FOR COMMUNITY-DWELLING OLDER ADULTS IN CHINA

    GSA 2024 abstract31 Dec 2024

Home hazards

downin humans1

1 study

  1. Live-life program decreases home hazards in humans (d = -0.504, P = 0.043).

    “Results indicated significant differences and moderate effect sizes on 3-meter walking speed (P< 0.001, d =-0.603) and home hazards (P=0.043, d=-0.504).”

    Human trialcommunity-dwelling older adults11 weeksn = 38

    PILOT OUTCOMES OF A FALL PREVENTION PROGRAM “LIVE-LIFE” FOR COMMUNITY-DWELLING OLDER ADULTS IN CHINA

    GSA 2024 abstract31 Dec 2024

Gait speed

upin humans1

1 study

  1. Live-life program improves gait speed in humans (d = -0.603, P < 0.001).

    “Results indicated significant differences and moderate effect sizes on 3-meter walking speed (P< 0.001, d =-0.603) and home hazards (P=0.043, d=-0.504).”

    Human trialcommunity-dwelling older adults11 weeksn = 38

    PILOT OUTCOMES OF A FALL PREVENTION PROGRAM “LIVE-LIFE” FOR COMMUNITY-DWELLING OLDER ADULTS IN CHINA

    GSA 2024 abstract31 Dec 2024

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