Lico

Lico has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 13, 2026: “RNA platform sustained gene silencing beyond the liver in mice”.

Intervention

1 paper studies it1 findingUpdated Oct 21, 2026

1 new paper in 30 daysSee all 1 papers on lico

At a glance

The findings reach mice, none yet in people. 1 lab.

1 lab

1 of 1 finding with company ties

Animals1

What did studies of lico find?

Studies of lico measured one outcome, target expression.

Target expression

downin mice1

1 study

Lico decreases target expression in mice (>90% target knockdown; ≥50% silencing for 6 months; measurable activity at 9 months).
“A single systemic dose in mice produced >90% target knockdown in skeletal muscle, heart, aorta, and adipose tissue”
Animalsskeletal muscle, heart, aorta, and adipose tissueA single systemic doseUp to 9 months
RNA platform sustained gene silencing beyond the liver in mice
Molecular therapy. Nucleic acidsOct 21, 2026

Latest

1 paper in 12 months

Molecular Therapy Nucleic AcidsNov 13

RNA platform sustained gene silencing beyond the liver in mice

One dose reduced target gene messages by more than 90% in several mouse tissues, with at least 50% silencing lasting six months.One dose reduced target gene messages by more than 90% in several mouse tissues, with at least 50% silencing lasting six months.

Mouse studyInterventions

Paper