Lentiviral TRPV4 gene delivery
Lentiviral TRPV4 gene delivery has been studied in 1 paper since 2016: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Mar 7, 2016: “Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging”.
1 paper studies it1 findingUpdated
- 1 lab in 1 country
- Funders: Anhui Medical University and 2 more
- Animals1
What did studies of Lentiviral TRPV4 gene delivery find?
1Studies of Lentiviral TRPV4 gene delivery measured 1 outcome; the most studied are mesenteric artery dilation (1 study).
Mesenteric artery dilation
upin rats1
1 study
Mesenteric artery dilation
upin rats1
Lentiviral TRPV4 gene delivery increases mesenteric artery dilation in rats.
“lentiviral vector delivery of TRPV4 increased TRPV4 expression level in aged MAECs and restored the flow- and 4α-PDD-induced vessel dilation in aged mesenteric arteries.”
Animalsflow or 4α-PDD stimulation; compared with lentiviral GFP treatmentlentiviral vectormesenteric artery
Scientific reports
Latest
Scientific Reports
Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging
Experiments in ratsInterventions