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Leg cycling

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Centre International de Recherche sur le Cancer
  • Human trial1

Outcomes

1

Peak oxygen consumption

upin humans1

1 study

  1. Leg cycling increases peak oxygen consumption in humans (~19% specific vs ~8% cross).

    “The amplitude of the increase in W(peak), VO(2peak) and O2P(peak) was significantly higher for specific than for cross tests ( approximately 19% vs. approximately 8 % in CYC”

    Human trial12-weekmalesn = 6

    Adaptations to endurance training in the healthy elderly: arm cranking versus leg cycling

    European journal of applied physiology24 Jun 2006

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