Ipsc-derived small extracellular vesicles

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Natural Science Foundation of China-China Academy of General Technology Joint Fund for Basic Research

Animals1

Outcomes

CISH

downin mice1

1 study

Ipsc-derived small extracellular vesicles inhibit CISH in mice.
“iPSC-sEVs inhibit the upregulation of CISH in senescent NK cells”
Animalsin senescent NK cells
iPSCs derived sEVs ameliorate NK cell senescence by targeting CISH-STAT3
Stem cell research & therapy12 Nov 2025

Latest

1 in 12 months

Stem Cell Research & Therapy13 Nov

iPSCs derived sEVs ameliorate NK cell senescence by targeting CISH-STAT3

Experiments in miceInterventions

Paper

Ipsc-derived small extracellular vesicles

Outcomes

Latest

iPSCs derived sEVs ameliorate NK cell senescence by targeting CISH-STAT3

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