Intrasplenic thymus regeneration

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: Fundamental Research Funds for the Central Universities and 1 more
  • Animals1

Outcomes

2

Functional human T cells

upin mice1

1 study
  1. Intrasplenic thymus regeneration increases functional human T cells in mice.

    Animalsin humanized animals

    Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T-Cell Immunity

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)25 Aug 2026

More on Functional human T cells

Protective responses to viral and tumor challenges

upin mice1

1 study
  1. Intrasplenic thymus regeneration improves protective responses to viral and tumor challenges in mice.

    Animalsin athymic nude, aged, thymectomized HSCT, and humanized mice

    Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T-Cell Immunity

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)25 Aug 2026

Associations

1

Graft-versus-host disease

downin mice1

1 study
  1. Intrasplenic thymus regeneration lowers the risk of graft-versus-host disease in mice.

    Animalsrelative to intramuscular implantation

    Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T-Cell Immunity

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)25 Aug 2026

More on Graft-versus-host disease

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