Intranasal corticosteroids
Intervention1 paper3 findings
- Humans1
Outcomes
1Bone mineral density
downin humans1Low certainty
1 study
Bone mineral density
downin humans1Low certainty
Intranasal corticosteroids decrease bone mineral density in humans.
Humansallergic rhinitismedian follow-up of 4.2 yearsfemales
Long-term intranasal corticosteroids vs. antihistamines and bone health in post-menopausal women with allergic rhinitis: a retrospective cohort study · Frontiers in medicine · 10 Aug 2026
Associations
2Fragility fractures
upin humans1HR 3.85Moderate certainty
1 study
Fragility fractures
upin humans1HR 3.85Moderate certainty
Intranasal corticosteroids raise the risk of fragility fractures in humans (adjusted HR 3.85 (95% CI = 1.45-10.24, p = 0.007)).
Humansallergic rhinitisfemales
Long-term intranasal corticosteroids vs. antihistamines and bone health in post-menopausal women with allergic rhinitis: a retrospective cohort study · Frontiers in medicine · 10 Aug 2026
Osteoporosis
upin humans1Low certainty
1 study
Osteoporosis
upin humans1Low certainty
Intranasal corticosteroids raise the risk of osteoporosis in humans (24.2% vs. 11.3%).
Humansallergic rhinitisfemales
Long-term intranasal corticosteroids vs. antihistamines and bone health in post-menopausal women with allergic rhinitis: a retrospective cohort study · Frontiers in medicine · 10 Aug 2026