Intensive care unit admission

1. Intensive care unit admission has no effect on mortality in humans (adjusted HR 1.08, 95% CI 0.83-1.41).

   “At the end of follow-up, there were 112 deaths of 232 patients (48.3%) who were admitted to the ICU, compared with 111 deaths of 232 patients (47.8%) who were not: adjusted HR 1.08, 95% CI 0.83-1.41, P = 0.573.”

   Humansafter elective major noncardiac surgerymedian 74 monthsn = 464

   Intensive Care Unit admission and long-term survival in older patients after elective major noncardiac surgery: A secondary analysis

   PloS one·Dec 11, 2025

2. Intensive care unit admission has no effect on mortality in humans (HR 1.17, 95% CI 0.95-1.46).

   “Survival was not significantly different between patients admitted in an ICU and an IMCU (HR 1.17, 95% CI 0.95-1.46).”

   Humanscritically ill older patients presenting at emergency departmentsn = 3,036

   Impact on 6-month outcomes of hospital trajectory in critically ill older patients: analysis of the ICE-CUB2 clinical trial

   Annals of intensive care·Jul 11, 2022

1. Intensive care unit admission has no effect on recurrence-free survival in humans.

   “Secondary endpoints, including recurrence-free survival and event-free survival, also did not differ significantly between groups.”

   Humansafter elective major noncardiac surgerymedian 74 monthsn = 464

   Intensive Care Unit admission and long-term survival in older patients after elective major noncardiac surgery: A secondary analysis

   PloS one·Dec 11, 2025

1. Intensive care unit admission has no effect on SPPB in humans.

   “Lack of association between ICU stay, age or sex with SPPB results differs from the results of other studies.”

   Humanspatients hospitalized with COVID-19n = 36

   Patient physical condition and functional sequelae following hospitalization with COVID-19: A cross-sectional observational study

   Medicine·Mar 28, 2025

More on SPPB

1. Intensive care unit admission decreases in-hospital mortality in humans (in-hospital death rates were 52.3% in Israel, 29.8% in Australia, and 22.1% in USA).

   “ICU admission of adults ≥ 80 years is associated with increased in-hospital survival compared to ward admission, but survival rates 2 years later are similar.”

   Humanscompared to ward admission

   Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study

   Annals of intensive care·Mar 4, 2022

1. Intensive care unit admission impairs physical function in humans.

   “In patients treated in the ICU, physical impairments as well as the activity level were significantly more pronounced compared to patients not treated in the ICU.”

   Humanshospitalized due to COVID-19

   Physical Function, Cognitive Function, and Daily Activities in Patients Hospitalized Due to COVID-19: A Descriptive Cross-Sectional Study in Sweden

   International journal of environmental research and public health·Nov 4, 2021

1. Intensive care unit admission impairs functional status in humans (median BI 100 points (IQR 85-100) at baseline vs 85 (IQR 60-100) at hospital discharge, P < .001).

   “ICU admission was associated with significant clinical deterioration (median BI 100 points (interquartile range (IQR) 85-100) at baseline vs 85 (IQR 60-100) at hospital discharge, P < .001).”

   Humansat hospital discharge vs baselinen = 110

   Functional Status and Quality of Life in Elderly Intensive Care Unit Survivors

   Journal of the American Geriatrics Society·Mar 1, 2016

1. Intensive care unit admission raises the risk of mortality in humans (HR, 1.03; 95% CI 1.02-1.04).

   “Patients surviving the first year remained at an increased risk compared to the general population, but much of this difference was attenuated after adjustment for baseline comorbidity (HR, 1.03; 95% CI 1.02-1.04).”

   Humanssurviving the first year after ICU admission, adjusted for baseline comorbidity

   The long-term conditional mortality rate in older ICU patients compared to the general population

   Critical care (London, England)·Nov 14, 2024

2. Intensive care unit admission is associated with mortality in humans (52% alive at 6 months).

   “Seventy-one percent of patients were still alive when released from ICU, and 52% were still alive after 6 months.”

   HumansICU admission6 monthsn = 239

   Prognosis of Very Elderly Patients after Intensive Care

   Journal of clinical medicine·Feb 9, 2022

3. Intensive care unit admission raises the risk of mortality in humans.

   “ASA classification, admission to the ICU, and the preoperative CRP levels showed an independent association with a poor overall survival.”

   Humanspostoperative hip fracture surgery

   C-reactive Protein Level, Admission to Intensive Care Unit, and High American Society of Anesthesiologists Score Affect Early and Late Postoperative Mortality in Geriatric Patients with Hip Fracture

   Hip & pelvis·Dec 1, 2021

1. Intensive care unit admission is associated with smoking in humans.

   “number of years smoking (P = .029) and days of hospitalization (P = .005).”

   Humanspatients hospitalized with COVID-19n = 36

   Patient physical condition and functional sequelae following hospitalization with COVID-19: A cross-sectional observational study

   Medicine·Mar 28, 2025

More on Smoking

1. Intensive care unit admission is associated with physical activity in humans.

   “There was a significant relationship between admission to the ICU and having a heart disease (P = .015), the level of physical activity (P = .049)”

   Humanspatients hospitalized with COVID-19n = 36

   Patient physical condition and functional sequelae following hospitalization with COVID-19: A cross-sectional observational study

   Medicine·Mar 28, 2025

1. Intensive care unit admission is associated with heart disease in humans.

   “There was a significant relationship between admission to the ICU and having a heart disease (P = .015)”

   Humanspatients hospitalized with COVID-19n = 36

   Patient physical condition and functional sequelae following hospitalization with COVID-19: A cross-sectional observational study

   Medicine·Mar 28, 2025

More on Heart disease

1. Intensive care unit admission is associated with hospital length of stay in humans (median 12.4 days (range 5.7-31 days)).

   “The median length of hospital stay was 12.4 days (range: 5.7-31 days; IQR: 11-17.6 days).”

   Reviewn = 16,859

   Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review

   Critical care (London, England)·Mar 13, 2025

1. Intensive care unit admission is associated with 1-year mortality in humans (mean 1-year mortality 45.6%).

   “The mean six-month and 1-year mortality rates were 38.6% and 45.6%, respectively.”

   Review1 yearn = 16,859

   Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review

   Critical care (London, England)·Mar 13, 2025

1. Intensive care unit admission is associated with hospital mortality in humans (median 25.55% (range 0%-62.5%)).

   “The median hospital mortality was 25.55% (range: 0%-62.5%; IQR: 15%-35.5%).”

   Reviewn = 16,859

   Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review

   Critical care (London, England)·Mar 13, 2025

1. Intensive care unit admission is associated with functional dependency in humans (17%).

   “Among the patients which were non-dependent before hospitalization, 17% became dependent.”

   Humansnon-dependent before hospitalization6 months

   Prognosis of Very Elderly Patients after Intensive Care

   Journal of clinical medicine·Feb 9, 2022